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Mapping the Specific Amino Acid Residues That Make Hamster DPP4 Functional as a Receptor for Middle East Respiratory Syndrome Coronavirus

The novel emerging coronavirus Middle East respiratory syndrome coronavirus (MERS-CoV) binds to its receptor, dipeptidyl peptidase 4 (DPP4), via 14 interacting amino acids. We previously showed that if the five interacting amino acids which differ between hamster and human DPP4 are changed to the re...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: van Doremalen, Neeltje, Miazgowicz, Kerri L., Munster, Vincent J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4934753/
https://ncbi.nlm.nih.gov/pubmed/27030263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.03267-15
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