Cryo-EM structure of rhinovirus C15a bound to its cadherin-related protein 3 receptor

Infection by Rhinovirus-C (RV-C), a species of Picornaviridae Enterovirus, is strongly associated with childhood asthma exacerbations. Cellular binding and entry by all RV-C, which trigger these episodes, is mediated by the first extracellular domain (EC1) of cadherin-related protein 3 (CDHR3), a su...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Sun, Yingyuan, Watters, Kelly, Hill, Marchel G., Fang, Qianglin, Liu, Yue, Kuhn, Richard J., Klose, Thomas, Rossmann, Michael G., Palmenberg, Ann C.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2020
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7104174/
https://ncbi.nlm.nih.gov/pubmed/32152109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1921640117
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