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Cadherin-related family member 3, a childhood asthma susceptibility gene product, mediates rhinovirus C binding and replication

Members of rhinovirus C (RV-C) species are more likely to cause wheezing illnesses and asthma exacerbations compared with other rhinoviruses. The cellular receptor for these viruses was heretofore unknown. We report here that expression of human cadherin-related family member 3 (CDHR3) enables the c...

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書誌詳細
出版年:Proc Natl Acad Sci U S A
主要な著者: Bochkov, Yury A., Watters, Kelly, Ashraf, Shamaila, Griggs, Theodor F., Devries, Mark K., Jackson, Daniel J., Palmenberg, Ann C., Gern, James E.
フォーマット: Artigo
言語:Inglês
出版事項: National Academy of Sciences 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4418890/
https://ncbi.nlm.nih.gov/pubmed/25848009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1421178112
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