Cadherin-related family member 3, a childhood asthma susceptibility gene product, mediates rhinovirus C binding and replication

Members of rhinovirus C (RV-C) species are more likely to cause wheezing illnesses and asthma exacerbations compared with other rhinoviruses. The cellular receptor for these viruses was heretofore unknown. We report here that expression of human cadherin-related family member 3 (CDHR3) enables the c...

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Dades bibliogràfiques
Publicat a:Proc Natl Acad Sci U S A
Autors principals: Bochkov, Yury A., Watters, Kelly, Ashraf, Shamaila, Griggs, Theodor F., Devries, Mark K., Jackson, Daniel J., Palmenberg, Ann C., Gern, James E.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2015
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4418890/
https://ncbi.nlm.nih.gov/pubmed/25848009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1421178112
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