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Cadherin-related family member 3, a childhood asthma susceptibility gene product, mediates rhinovirus C binding and replication

Members of rhinovirus C (RV-C) species are more likely to cause wheezing illnesses and asthma exacerbations compared with other rhinoviruses. The cellular receptor for these viruses was heretofore unknown. We report here that expression of human cadherin-related family member 3 (CDHR3) enables the c...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Bochkov, Yury A., Watters, Kelly, Ashraf, Shamaila, Griggs, Theodor F., Devries, Mark K., Jackson, Daniel J., Palmenberg, Ann C., Gern, James E.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4418890/
https://ncbi.nlm.nih.gov/pubmed/25848009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1421178112
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