Cadherin-related family member 3, a childhood asthma susceptibility gene product, mediates rhinovirus C binding and replication

Members of rhinovirus C (RV-C) species are more likely to cause wheezing illnesses and asthma exacerbations compared with other rhinoviruses. The cellular receptor for these viruses was heretofore unknown. We report here that expression of human cadherin-related family member 3 (CDHR3) enables the c...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Proc Natl Acad Sci U S A
Prif Awduron: Bochkov, Yury A., Watters, Kelly, Ashraf, Shamaila, Griggs, Theodor F., Devries, Mark K., Jackson, Daniel J., Palmenberg, Ann C., Gern, James E.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 2015
Pynciau:
Biological Sciences
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4418890/
https://ncbi.nlm.nih.gov/pubmed/25848009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1421178112
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