Cystic renal‐epithelial derived induced pluripotent stem cells from polycystic kidney disease patients

Autosomal‐dominant polycystic kidney disease (ADPKD) is the most common inherited kidney disease, leading to kidney failure in most patients. In approximately 85% of cases, the disease is caused by mutations in PKD1. How dysregulation of PKD1 leads to cyst formation on a molecular level is unknown....

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Bibliografiset tiedot
Julkaisussa:Stem Cells Transl Med
Päätekijät: Kenter, Annegien T., Rentmeester, Eveline, van Riet, Job, Boers, Ruben, Boers, Joachim, Ghazvini, Mehrnaz, Xavier, Vanessa J., van Leenders, Geert J.L.H., Verhagen, Paul C.M.S., van Til, Marjan E., Eussen, Bert, Losekoot, Monique, de Klein, Annelies, Peters, Dorien J.M., van IJcken, Wilfred F.J., van de Werken, Harmen J.G., Zietse, Robert, Hoorn, Ewout J., Jansen, Gert, Gribnau, Joost H.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: John Wiley & Sons, Inc. 2020
Aiheet:
Pluripotent Stem Cells
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7103626/
https://ncbi.nlm.nih.gov/pubmed/32163234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/sctm.18-0283
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