Cystic renal‐epithelial derived induced pluripotent stem cells from polycystic kidney disease patients

Autosomal‐dominant polycystic kidney disease (ADPKD) is the most common inherited kidney disease, leading to kidney failure in most patients. In approximately 85% of cases, the disease is caused by mutations in PKD1. How dysregulation of PKD1 leads to cyst formation on a molecular level is unknown....

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Detalhes bibliográficos
Publicado no:Stem Cells Transl Med
Main Authors: Kenter, Annegien T., Rentmeester, Eveline, van Riet, Job, Boers, Ruben, Boers, Joachim, Ghazvini, Mehrnaz, Xavier, Vanessa J., van Leenders, Geert J.L.H., Verhagen, Paul C.M.S., van Til, Marjan E., Eussen, Bert, Losekoot, Monique, de Klein, Annelies, Peters, Dorien J.M., van IJcken, Wilfred F.J., van de Werken, Harmen J.G., Zietse, Robert, Hoorn, Ewout J., Jansen, Gert, Gribnau, Joost H.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons, Inc. 2020
Assuntos:
Pluripotent Stem Cells
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7103626/
https://ncbi.nlm.nih.gov/pubmed/32163234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/sctm.18-0283
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