Importance of cholesterol-rich membrane microdomains in the interaction of the S protein of SARS-coronavirus with the cellular receptor angiotensin-converting enzyme 2

Cholesterol present in the plasma membrane of target cells has been shown to be important for the infection by SARS-CoV. We show that cholesterol depletion by treatment with methyl-β-cyclodextrin (mβCD) affects infection by SARS-CoV to the same extent as infection by vesicular stomatitis virus-based...

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Publicado no:Virology
Main Authors: Glende, Joerg, Schwegmann-Wessels, Christel, Al-Falah, Marwan, Pfefferle, Susanne, Qu, Xiuxia, Deng, Hongkui, Drosten, Christian, Naim, Hassan Y., Herrler, Georg
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier Inc. 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7103374/
https://ncbi.nlm.nih.gov/pubmed/18814896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2008.08.026
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