A Novel Sorting Signal for Intracellular Localization Is Present in the S Protein of a Porcine Coronavirus but Absent from Severe Acute Respiratory Syndrome-associated Coronavirus

Coronaviruses (CoV) mature by a budding process at intracellular membranes. Here we showed that the major surface protein S of a porcine CoV (transmissible gastroenteritis virus) is not transported to the cell surface but is retained intracellularly. Site-directed mutagenesis indicated that a tyrosi...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Schwegmann-Wessels, Christel, Al-Falah, Marwan, Escors, David, Wang, Zai, Zimmer, Gert, Deng, Hongkui, Enjuanes, Luis, Naim, Hassan Y., Herrler, Georg
Formato: Artigo
Idioma:Inglês
Publicado em: ASBMB. Currently published by Elsevier Inc; originally published by American Society for Biochemistry and Molecular Biology. 2004
Assuntos:
Membrane Transport, Structure, Function, and Biogenesis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8060824/
https://ncbi.nlm.nih.gov/pubmed/15304515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M407233200
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