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Identification of anti-viral activity of the cardenolides, Na(+)/K(+)-ATPase inhibitors, against porcine transmissible gastroenteritis virus

A series of naturally occurring cardenolides that exhibit potent anti-transmissible gastroenteritis virus (TGEV) activity in swine testicular (ST) cells has been identified. In an immunofluorescence assay, these cardenolides were found to diminish the expressions of TGEV nucleocapsid and spike prote...

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Publicat a:Toxicol Appl Pharmacol
Autors principals: Yang, Cheng-Wei, Chang, Hsin-Yu, Hsu, Hsing-Yu, Lee, Yue-Zhi, Chang, Hsun-Shuo, Chen, Ih-Sheng, Lee, Shiow-Ju
Format: Artigo
Idioma:Inglês
Publicat: Elsevier Inc. 2017
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7103123/
https://ncbi.nlm.nih.gov/pubmed/28438630
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.taap.2017.04.017
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