Dopamine deficiency reduces striatal cholinergic interneuron function in models of Parkinson’s disease

Motor and cognitive functions depend on the coordinated interactions between dopamine (DA) and acetylcholine (ACh) at striatal synapses. Increased ACh availability was assumed to accompany DA deficiency based on the outcome of pharmacological treatments and measurements in animals that were critical...

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Vydáno v:Neuron
Hlavní autoři: McKinley, Jonathan W., Shi, Ziqing, Kawikova, Ivana, Hur, Matthew, Bamford, Ian J., Sudarsana Devi, Suma Priya, Vahedipour, Annie, Darvas, Martin, Bamford, Nigel S.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2019
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7102938/
https://ncbi.nlm.nih.gov/pubmed/31324539
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2019.06.013
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