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Airway proteases: an emerging drug target for influenza and other respiratory virus infections

To enter into airway epithelial cells, influenza, parainfluenza- and coronaviruses rely on host cell proteases for activation of the viral protein involved in membrane fusion. One protease, transmembrane protease serine 2 (TMPRSS2) was recently proven to be crucial for hemagglutinin cleavage of some...

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Dettagli Bibliografici
Pubblicato in:Curr Opin Virol
Autori principali: Laporte, Manon, Naesens, Lieve
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Authors. Published by Elsevier B.V. 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7102789/
https://ncbi.nlm.nih.gov/pubmed/28414992
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.coviro.2017.03.018
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