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Airway proteases: an emerging drug target for influenza and other respiratory virus infections

To enter into airway epithelial cells, influenza, parainfluenza- and coronaviruses rely on host cell proteases for activation of the viral protein involved in membrane fusion. One protease, transmembrane protease serine 2 (TMPRSS2) was recently proven to be crucial for hemagglutinin cleavage of some...

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Библиографические подробности
Опубликовано в: :Curr Opin Virol
Главные авторы: Laporte, Manon, Naesens, Lieve
Формат: Artigo
Язык:Inglês
Опубликовано: The Authors. Published by Elsevier B.V. 2017
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7102789/
https://ncbi.nlm.nih.gov/pubmed/28414992
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.coviro.2017.03.018
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