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Implications of altered replication fidelity on the evolution and pathogenesis of coronaviruses

RNA virus evolution results from viral replication fidelity and mutational robustness in combination with selection. Recent studies have confirmed the impact of increased fidelity on RNA virus replication and pathogenesis; however, the impact of decreased fidelity is less defined. Coronaviruses have...

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Detalhes bibliográficos
Publicado no:Curr Opin Virol
Main Authors: Smith, Everett C, Denison, Mark R
Formato: Artigo
Idioma:Inglês
Publicado em: Published by Elsevier B.V. 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7102773/
https://ncbi.nlm.nih.gov/pubmed/22857992
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.coviro.2012.07.005
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