Mitochondria-targeted triphenylphosphonium-based compounds do not affect estrogen receptor α

BACKGROUND: Targeting negatively charged mitochondria is often achieved using triphenylphosphonium (TPP) cations. These cationic vehicles may possess biological activity, and a docking study indicates that TPP-moieties may act as modulators of signaling through the estrogen receptor α (ERα). Moreove...

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Detalles Bibliográficos
Publicado en:PeerJ
Main Authors: Zinovkina, Ludmila A., Galivondzhyan, Alina K., Prikhodko, Anastasia S., Galkin, Ivan I., Zinovkin, Roman A.
Formato: Artigo
Idioma:Inglês
Publicado: PeerJ Inc. 2020
Assuntos:
Biochemistry
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7102506/
https://ncbi.nlm.nih.gov/pubmed/32257641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7717/peerj.8803
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