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Intracellular versus extracellular granzyme B in immunity and disease: challenging the dogma
The cytotoxic granzyme B (GrB)/perforin pathway has been traditionally viewed as a primary mechanism that is used by cytotoxic lymphocytes to eliminate allogeneic, virally infected and/or transformed cells. Although originally proposed to have intracellular and extracellular functions, upon the disc...
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| Publicado no: | Lab Invest |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group US
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7102238/ https://ncbi.nlm.nih.gov/pubmed/19770840 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/labinvest.2009.91 |
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