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Heterozygous rare genetic variants in non-syndromic early-onset obesity

BACKGROUND: Obesity is a very heterogeneous disorder at both the clinical and molecular levels and with high heritability. Several monogenic forms and genes with strong effects have been identified for non-syndromic severe obesity. Novel therapeutic interventions are in development for some genetic...

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Dettagli Bibliografici
Pubblicato in:Int J Obes (Lond)
Autori principali: Serra-Juhé, Clara, Martos-Moreno, Gabriel Á., Bou de Pieri, Francesc, Flores, Raquel, Chowen, Julie A., Pérez-Jurado, Luis A., Argente, Jesús
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7101277/
https://ncbi.nlm.nih.gov/pubmed/30926952
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41366-019-0357-5
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