Novel genes involved in severe early-onset obesity revealed by rare copy number and sequence variants

Obesity is a multifactorial disorder with high heritability (50–75%), which is probably higher in early-onset and severe cases. Although rare monogenic forms and several genes and regions of susceptibility, including copy number variants (CNVs), have been described, the genetic causes underlying the...

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Detalhes bibliográficos
Publicado no:PLoS Genet
Main Authors: Serra-Juhé, Clara, Martos-Moreno, Gabriel Á., Bou de Pieri, Francesc, Flores, Raquel, González, Juan R., Rodríguez-Santiago, Benjamín, Argente, Jesús, Pérez-Jurado, Luis A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5443539/
https://ncbi.nlm.nih.gov/pubmed/28489853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1006657
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