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Novel genes involved in severe early-onset obesity revealed by rare copy number and sequence variants
Obesity is a multifactorial disorder with high heritability (50–75%), which is probably higher in early-onset and severe cases. Although rare monogenic forms and several genes and regions of susceptibility, including copy number variants (CNVs), have been described, the genetic causes underlying the...
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| Veröffentlicht in: | PLoS Genet |
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| Hauptverfasser: | , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Public Library of Science
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5443539/ https://ncbi.nlm.nih.gov/pubmed/28489853 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1006657 |
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