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Regnase-1 degradation is crucial for IL-33– and IL-25–mediated ILC2 activation
Group 2 innate lymphoid cells (ILC2s) are a critical innate source of type 2 cytokines in allergic inflammation. Although ILC2s are recognized as a critical cell population in the allergic inflammation, the regulatory mechanism(s) of ILC2s are less well understood. Here, we show that Regnase-1, an i...
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| Izdano u: | JCI Insight |
|---|---|
| Glavni autori: | , , , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Society for Clinical Investigation
2020
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7101157/ https://ncbi.nlm.nih.gov/pubmed/31990689 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.131480 |
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