Regnase-1 degradation is crucial for IL-33– and IL-25–mediated ILC2 activation

Group 2 innate lymphoid cells (ILC2s) are a critical innate source of type 2 cytokines in allergic inflammation. Although ILC2s are recognized as a critical cell population in the allergic inflammation, the regulatory mechanism(s) of ILC2s are less well understood. Here, we show that Regnase-1, an i...

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Detalhes bibliográficos
Publicado no:JCI Insight
Main Authors: Matsushita, Kazufumi, Tanaka, Hiroki, Yasuda, Koubun, Adachi, Takumi, Fukuoka, Ayumi, Akasaki, Shoko, Koida, Atsuhide, Kuroda, Etsushi, Akira, Shizuo, Yoshimoto, Tomohiro
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2020
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7101157/
https://ncbi.nlm.nih.gov/pubmed/31990689
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.131480
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