Fibroblast subtypes define a metastatic matrisome in breast cancer

Small primary breast cancers can show surprisingly high potential for metastasis. Clinical decision-making for tumor aggressiveness, including molecular profiling, relies primarily on analysis of the cancer cells. Here we show that this analysis is insufficient — that the stromal microenvironment of...

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Publicado en:JCI Insight
Autores principales: Brechbuhl, Heather M., Barrett, Alexander S., Kopin, Etana, Hagen, Jaime C., Han, Amy L., Gillen, Austin E., Finlay-Schultz, Jessica, Cittelly, Diana M., Owens, Philip, Horwitz, Kathryn B., Sartorius, Carol A., Hansen, Kirk, Kabos, Peter
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Clinical Investigation 2020
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7101155/
https://ncbi.nlm.nih.gov/pubmed/32045383
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.130751
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