FPR-1 is an important regulator of neutrophil recruitment and a tissue-specific driver of pulmonary fibrosis

Neutrophils are the most abundant inflammatory cells at the earliest stages of wound healing and play important roles in wound repair and fibrosis. Formyl peptide receptor 1 (FPR-1) is abundantly expressed on neutrophils and has been shown to regulate their function, yet the importance of FPR-1 in f...

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Veröffentlicht in:JCI Insight
Hauptverfasser: Leslie, Jack, Millar, Ben J.M., del Carpio Pons, Alicia, Burgoyne, Rachel A., Frost, Joseph D., Barksby, Ben S., Luli, Saimir, Scott, Jon, Simpson, A. John, Gauldie, Jack, Murray, Lynne A., Finch, Donna K., Carruthers, Alan M., Ferguson, John, Sleeman, Matthew A., Rider, David, Howarth, Rachel, Fox, Christopher, Oakley, Fiona, Fisher, Andrew J., Mann, Derek A., Borthwick, Lee A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Clinical Investigation 2020
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7101152/
https://ncbi.nlm.nih.gov/pubmed/32102985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.125937
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