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Spatial chromatin organization and gene regulation at the nuclear lamina

The nuclear lamina (NL) consists of a thin meshwork of lamins and associated proteins that lines the inner nuclear membrane (INM). In metazoan nuclei, a large proportion of the genome contacts the NL in broad lamina-associated domains (LADs). Contacts of the NL with the genome are believed to aid th...

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Publicado en:Curr Opin Genet Dev
Autores principales: Guerreiro, Isabel, Kind, Jop
Formato: Artigo
Lenguaje:Inglês
Publicado: 2019
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7100903/
https://ncbi.nlm.nih.gov/pubmed/31112905
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.gde.2019.04.008
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