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Spatial chromatin organization and gene regulation at the nuclear lamina

The nuclear lamina (NL) consists of a thin meshwork of lamins and associated proteins that lines the inner nuclear membrane (INM). In metazoan nuclei, a large proportion of the genome contacts the NL in broad lamina-associated domains (LADs). Contacts of the NL with the genome are believed to aid th...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Curr Opin Genet Dev
Main Authors: Guerreiro, Isabel, Kind, Jop
Format: Artigo
Jezik:Inglês
Izdano: 2019
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7100903/
https://ncbi.nlm.nih.gov/pubmed/31112905
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.gde.2019.04.008
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