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Development and validation of an HILIC–MS/MS method by one-step precipitation for chloroquine in miniature pig plasma
BACKGROUND: Quantification of polar compounds such as chloroquine by revered-phase LC is a challenge because of poor retention and silanol interactions with stationary phase. Strong ion-pairing reagents added to mobile phases to improve reversed-phase retention and improve peak shape can be harmful...
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| Publicado en: | Bioanalysis |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Future Science Ltd
2016
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7099630/ https://ncbi.nlm.nih.gov/pubmed/27211608 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4155/bio-2015-0032 |
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