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Loss of circadian gene Bmal1 in the collecting duct lowers blood pressure in male, but not female, mice
Kidney function follows a 24-h rhythm subject to regulation by circadian genes including the transcription factor Bmal1. A high-salt diet induces a phase shift in Bmal1 expression in the renal inner medulla that is dependent on endothelin type B (ET(B)) receptors. Furthermore, ET(B) receptor-mediate...
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| Publicado no: | Am J Physiol Renal Physiol |
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| Main Authors: | , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Physiological Society
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7099501/ https://ncbi.nlm.nih.gov/pubmed/31904281 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00364.2019 |
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