A Shared Regulatory Element Controls the Initiation of Tcf7 Expression During Early T Cell and Innate Lymphoid Cell Developments

The transcription factor TCF-1 (encoded by Tcf7) plays critical roles in several lineages of hematopoietic cells. In this study, we examined the molecular basis for Tcf7 regulation in T cells, innate lymphoid cells, and migratory conventional dendritic cells that we find express Tcf7. We identified...

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Publicado en:Front Immunol
Autores principales: Harly, Christelle, Kenney, Devin, Wang, Yueqiang, Ding, Yi, Zhao, Yongge, Awasthi, Parirokh, Bhandoola, Avinash
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2020
Materias:
Immunology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7099406/
https://ncbi.nlm.nih.gov/pubmed/32265924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.00470
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