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TCF-1 upregulation identifies early innate lymphoid progenitors in the bone marrow

The cellular and molecular events that drive early innate lympoid cell (ILC) development remain poorly understood. We show that transcription factor TCF-1 is required for the efficient generation of all known adult ILC subsets and their precursors. Using novel reporter mice, we identified a new subs...

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Détails bibliographiques
Publié dans:Nat Immunol
Auteurs principaux: Yang, Qi, Li, Fengyin, Harly, Christelle, Xing, Shaojun, Ye, Longyun, Xia, Xuefeng, Wang, Haikun, Wang, Xinxin, Yu, Shuyang, Zhou, Xinyuan, Cam, Maggie, Xue, Hai-Hui, Bhandoola, Avinash
Format: Artigo
Langue:Inglês
Publié: 2015
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4575643/
https://ncbi.nlm.nih.gov/pubmed/26280998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.3248
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