Microglial depletion under thalamic hemorrhage ameliorates mechanical allodynia and suppresses aberrant axonal sprouting

Central poststroke pain (CPSP) is one of the neuropathic pain syndromes that can occur following stroke involving the somatosensory system. However, the underlying mechanism of CPSP remains largely unknown. Here, we established a CPSP mouse model by inducing a focal hemorrhage in the thalamic ventro...

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Опубликовано в: :JCI Insight
Главные авторы: Hiraga, Shin-ichiro, Itokazu, Takahide, Hoshiko, Maki, Takaya, Hironobu, Nishibe, Mariko, Yamashita, Toshihide
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Clinical Investigation 2020
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7098795/
https://ncbi.nlm.nih.gov/pubmed/32051342
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.131801
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