Microglial depletion under thalamic hemorrhage ameliorates mechanical allodynia and suppresses aberrant axonal sprouting

Central poststroke pain (CPSP) is one of the neuropathic pain syndromes that can occur following stroke involving the somatosensory system. However, the underlying mechanism of CPSP remains largely unknown. Here, we established a CPSP mouse model by inducing a focal hemorrhage in the thalamic ventro...

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Detalhes bibliográficos
Publicado no:JCI Insight
Main Authors: Hiraga, Shin-ichiro, Itokazu, Takahide, Hoshiko, Maki, Takaya, Hironobu, Nishibe, Mariko, Yamashita, Toshihide
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2020
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7098795/
https://ncbi.nlm.nih.gov/pubmed/32051342
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.131801
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