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Stochastic simulation and statistical inference platform for visualization and estimation of transcriptional kinetics

Recent advances in single-molecule fluorescent imaging have enabled quantitative measurements of transcription at a single gene copy, yet an accurate understanding of transcriptional kinetics is still lacking due to the difficulty of solving detailed biophysical models. Here we introduce a stochasti...

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Veröffentlicht in:PLoS One
Hauptverfasser: Gorin, Gennady, Wang, Mengyu, Golding, Ido, Xu, Heng
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7098607/
https://ncbi.nlm.nih.gov/pubmed/32214380
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0230736
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