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Fosmidomycin Biosynthesis Diverges from Related Phosphonate Natural Products

Fosmidomycin and related molecules comprise a family of phosphonate natural products with potent antibacterial, antimalarial and herbicidal activities. To understand the biosynthesis of these compounds, we characterized the fosmidomycin producer, Streptomyces lavendulae, using biochemical and geneti...

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Publicat a:Nat Chem Biol
Autors principals: Parkinson, Elizabeth I., Erb, Annette, Eliot, Andrew C., Ju, Kou-San, Metcalf, William W.
Format: Artigo
Idioma:Inglês
Publicat: 2019
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7098449/
https://ncbi.nlm.nih.gov/pubmed/31451762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41589-019-0343-1
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