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Wood Smoke Particles Stimulate MUC5AC Overproduction by Human Bronchial Epithelial Cells Through TRPA1 and EGFR Signaling

Mucus hypersecretion is a pathological feature of acute inflammatory and chronic obstructive pulmonary diseases. Exposure to air pollutants can be a cause of pathological mucus overproduction, but mechanisms by which different forms of air pollutants elicit this response are not fully understood. In...

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Publicado en:Toxicol Sci
Autores principales: Memon, Tosifa A, Nguyen, Nam D, Burrell, Katherine L, Scott, Abigail F, Almestica-Roberts, Marysol, Rapp, Emmanuel, Deering-Rice, Cassandra E, Reilly, Christopher A
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2020
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7098379/
https://ncbi.nlm.nih.gov/pubmed/31944254
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfaa006
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