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Meta-Analysis of Nanoparticle Delivery to Tumors Using a Physiologically Based Pharmacokinetic Modeling and Simulation Approach

[Image: see text] Numerous studies have engineered nanoparticles with different physicochemical properties to enhance the delivery efficiency to solid tumors, yet the mean and median delivery efficiencies are only 1.48% and 0.70% of the injected dose (%ID), respectively, according to a study using a...

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Detalhes bibliográficos
Publicado no:ACS Nano
Main Authors: Cheng, Yi-Hsien, He, Chunla, Riviere, Jim E., Monteiro-Riviere, Nancy A., Lin, Zhoumeng
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2020
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7098057/
https://ncbi.nlm.nih.gov/pubmed/32078303
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsnano.9b08142
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