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Probabilistic risk assessment of gold nanoparticles after intravenous administration by integrating in vitro and in vivo toxicity with physiologically based pharmacokinetic modeling

This study aimed to conduct an integrated and probabilistic risk assessment of gold nanoparticles (AuNPs) based on recently published in vitro and in vivo toxicity studies coupled to a physiologically based pharmacokinetic (PBPK) model. Dose–response relationships were characterized based on cell vi...

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Bibliografiske detaljer
Udgivet i:Nanotoxicology
Main Authors: Cheng, Yi-Hsien, Riviere, Jim E., Monteiro-Riviere, Nancy A., Lin, Zhoumeng
Format: Artigo
Sprog:Inglês
Udgivet: 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6051695/
https://ncbi.nlm.nih.gov/pubmed/29658401
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/17435390.2018.1459922
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