Downregulation of Nitric Oxide Collaborated with Radiotherapy to Promote Anti-Tumor Immune Response via Inducing CD8+ T Cell Infiltration

The production of nitric oxide (NO) is a key feature of immunosuppressive myeloid cells, which impair T cell activation and proliferation via reversibly blocking interleukin-2 receptor signaling. NO is mainly produced from L-arginine by inducible NO synthase (iNOS). Moreover, L-arginine is an essent...

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Detalles Bibliográficos
Publicado en:Int J Biol Sci
Main Authors: Xu, Jieyu, Luo, Yuan, Yuan, Cheng, Han, Linzhi, Wu, Qiuji, Xu, Liexi, Gao, Yuke, Sun, Yingming, Ma, Shijing, Tang, Guiliang, Li, Shuying, Sun, Wenjie, Gong, Yan, Xie, Conghua
Formato: Artigo
Idioma:Inglês
Publicado: Ivyspring International Publisher 2020
Assuntos:
Research Paper
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7097922/
https://ncbi.nlm.nih.gov/pubmed/32226302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/ijbs.41653
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