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Current prospects for RNA interference-based therapies

RNA interference (RNAi) is a powerful approach for reducing expression of endogenously expressed proteins. It is widely used for biological applications and is being harnessed to silence mRNAs encoding pathogenic proteins for therapy. Various methods — including delivering RNA oligonucleotides and e...

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Bibliografiske detaljer
Udgivet i:Nat Rev Genet
Main Authors: Davidson, Beverly L., McCray, Paul B.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7097665/
https://ncbi.nlm.nih.gov/pubmed/21499294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrg2968
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