Fibroblastic reticular cells regulate intestinal inflammation via IL-15-mediated control of group 1 ILCs

Fibroblastic reticular cells (FRCs) of secondary lymphoid organs form distinct niches for interaction with hematopoietic cells. We found here that production of the cytokine IL-15 by FRCs was essential for the maintenance of group 1 innate lymphoid cells (ILCs) in Peyer's patches and mesenteric...

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Veröffentlicht in:Nat Immunol
Hauptverfasser: Gil-Cruz, Cristina, Perez-Shibayama, Christian, Onder, Lucas, Chai, Qian, Cupovic, Jovana, Cheng, Hung-Wei, Novkovic, Mario, Lang, Philipp A, Geuking, Markus B, McCoy, Kathy D, Abe, Shinya, Cui, Guangwei, Ikuta, Koichi, Scandella, Elke, Ludewig, Burkhard
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group US 2016
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7097164/
https://ncbi.nlm.nih.gov/pubmed/27798617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.3566
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