Origin and differentiation trajectories of fibroblastic reticular cells in the splenic white pulp

The splenic white pulp is underpinned by poorly characterized stromal cells that demarcate distinct immune cell microenvironments. Here we establish fibroblastic reticular cell (FRC)-specific fate-mapping in mice to define their embryonic origin and differentiation trajectories. Our data show that a...

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Publicat a:Nat Commun
Autors principals: Cheng, Hung-Wei, Onder, Lucas, Novkovic, Mario, Soneson, Charlotte, Lütge, Mechthild, Pikor, Natalia, Scandella, Elke, Robinson, Mark D., Miyazaki, Jun-ichi, Tersteegen, Anne, Sorg, Ursula, Pfeffer, Klaus, Rülicke, Thomas, Hehlgans, Thomas, Ludewig, Burkhard
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2019
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6465367/
https://ncbi.nlm.nih.gov/pubmed/30988302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-09728-3
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