Dampened NLRP3-mediated inflammation in bats and implications for a special viral reservoir host

Bats are special in their ability to host emerging viruses. As the only flying mammal, bats endure high metabolic rates yet exhibit elongated lifespans. It is currently unclear whether these unique features are interlinked. The important inflammasome sensor, NLR family pyrin domain containing 3 (NLR...

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Publicado en:Nat Microbiol
Autores principales: Ahn, Matae, Anderson, Danielle E., Zhang, Qian, Tan, Chee Wah, Lim, Beng Lee, Luko, Katarina, Wen, Ming, Chia, Wan Ni, Mani, Shailendra, Wang, Loo Chien, Ng, Justin Han Jia, Sobota, Radoslaw M., Dutertre, Charles-Antoine, Ginhoux, Florent, Shi, Zheng-Li, Irving, Aaron T., Wang, Lin-Fa
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group UK 2019
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7096966/
https://ncbi.nlm.nih.gov/pubmed/30804542
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41564-019-0371-3
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