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Complementary regulation of caspase-1 and IL-1β reveals additional mechanisms of dampened inflammation in bats
Bats have emerged as unique mammalian vectors harboring a diverse range of highly lethal zoonotic viruses with minimal clinical disease. Despite having sustained complete genomic loss of AIM2, regulation of the downstream inflammasome response in bats is unknown. AIM2 sensing of cytoplasmic DNA trig...
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| Veröffentlicht in: | Proc Natl Acad Sci U S A |
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| Hauptverfasser: | , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
2020
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7682399/ https://ncbi.nlm.nih.gov/pubmed/33106404 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2003352117 |
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