Urine Assay to Measure Tenofovir Concentrations in Patients Taking Tenofovir Alafenamide

Background: HIV pre-exposure prophylaxis (PrEP) with tenofovir/emtricitabine is effective when taken daily. Previously, we developed a urine assay capable of detecting the prodrug tenofovir (TFV) in patients taking tenofovir disoproxil fumarate (TDF)-based PrEP. However, tenofovir alafenamide (TAF)...

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Bibliographic Details
Published in:Front Pharmacol
Main Authors: Lalley-Chareczko, Linden, Hiserodt, Emily, Moorthy, Ganesh, Zuppa, Athena, Mounzer, Karam, Koenig, Helen
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2020
Subjects:
Pharmacology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7096572/
https://ncbi.nlm.nih.gov/pubmed/32265700
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2020.00286
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