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A subset of SMN complex members have a specific role in tissue regeneration via ERBB pathway-mediated proliferation

Spinal muscular atrophy (SMA) is the most common genetic disease in children. SMA is generally caused by mutations in the gene SMN1. The survival of motor neurons (SMN) complex consists of SMN1, Gemins (2–8), and Strap/Unrip. We previously demonstrated smn1 and gemin5 inhibited tissue regeneration i...

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Detalhes bibliográficos
Publicado no:NPJ Regen Med
Main Authors: Pei, Wuhong, Xu, Lisha, Chen, Zelin, Slevin, Claire C., Pettie, Kade P., Wincovitch, Stephen, Burgess, Shawn M.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7096462/
https://ncbi.nlm.nih.gov/pubmed/32218991
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41536-020-0089-0
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