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Safety and Efficacy of Naldemedine for the Treatment of Opioid-Induced Constipation in Patients with Chronic Non-Cancer Pain Receiving Opioid Therapy: A Subgroup Analysis of Patients ≥ 65 Years of Age

BACKGROUND: Opioid-induced constipation (OIC), the most common side effect of opioid treatment, is under-recognized and undertreated in older patients. Naldemedine, an oral, peripherally acting μ-opioid receptor antagonist (PAMORA), is approved in Japan, the United States, and the European Union for...

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Detalhes bibliográficos
Publicado no:Drugs Aging
Main Authors: Wild, James, Webster, Lynn, Yamada, Tadaaki, Hale, Martin
Formato: Artigo
Idioma:Inglês
Publicado em: Springer International Publishing 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7096364/
https://ncbi.nlm.nih.gov/pubmed/32086791
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40266-020-00753-2
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