Extra-mitochondrial citrate synthase initiates calcium oscillation and suppresses age-dependent sperm dysfunction

Men and women become infertile with age, but the mechanism of declining male fertility, more specifically, the decrease in in sperm quality, is not well known. Citrate synthase (CS) is a core enzyme of the mitochondrial tricarboxylic acid (TCA) cycle, which directly controls cellular function. Extra...

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Publicado no:Lab Invest
Main Authors: Kang, Woojin, Harada, Yuichirou, Yamatoya, Kenji, Kawano, Natsuko, Kanai, Seiya, Miyamoto, Yoshitaka, Nakamura, Akihiro, Miyado, Mami, Hayashi, Yoshiki, Kuroki, Yoko, Saito, Hidekazu, Iwao, Yasuhiro, Umezawa, Akihiro, Miyado, Kenji
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group US 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7096335/
https://ncbi.nlm.nih.gov/pubmed/31857692
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41374-019-0353-3
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