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The insulator functions of the Drosophila polydactyl C2H2 zinc finger protein CTCF: Necessity versus sufficiency

In mammals, a C2H2 zinc finger (C2H2) protein, CTCF, acts as the master regulator of chromosomal architecture and of the expression of Hox gene clusters. Like mammalian CTCF, the Drosophila homolog, dCTCF, localizes to boundaries in the bithorax complex (BX-C). Here, we have determined the minimal r...

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Publicat a:Sci Adv
Autors principals: Kyrchanova, Olga, Maksimenko, Oksana, Ibragimov, Airat, Sokolov, Vladimir, Postika, Nikolay, Lukyanova, Maria, Schedl, Paul, Georgiev, Pavel
Format: Artigo
Idioma:Inglês
Publicat: American Association for the Advancement of Science 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7096168/
https://ncbi.nlm.nih.gov/pubmed/32232161
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aaz3152
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