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Streptavidin/biotin: Tethering geometry defines unbinding mechanics

Macromolecules tend to respond to applied forces in many different ways. Chemistry at high shear forces can be intriguing, with relatively soft bonds becoming very stiff in specific force-loading geometries. Largely used in bionanotechnology, an important case is the streptavidin (SA)/biotin interac...

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書目詳細資料
發表在:Sci Adv
Main Authors: Sedlak, Steffen M., Schendel, Leonard C., Gaub, Hermann E., Bernardi, Rafael C.
格式: Artigo
語言:Inglês
出版: American Association for the Advancement of Science 2020
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7096159/
https://ncbi.nlm.nih.gov/pubmed/32232150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aay5999
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