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Streptavidin/biotin: Tethering geometry defines unbinding mechanics

Macromolecules tend to respond to applied forces in many different ways. Chemistry at high shear forces can be intriguing, with relatively soft bonds becoming very stiff in specific force-loading geometries. Largely used in bionanotechnology, an important case is the streptavidin (SA)/biotin interac...

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Bibliografiske detaljer
Udgivet i:Sci Adv
Main Authors: Sedlak, Steffen M., Schendel, Leonard C., Gaub, Hermann E., Bernardi, Rafael C.
Format: Artigo
Sprog:Inglês
Udgivet: American Association for the Advancement of Science 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7096159/
https://ncbi.nlm.nih.gov/pubmed/32232150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aay5999
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