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The virulence of mouse hepatitis virus strain A59 is not dependent on efficient spike protein cleavage and cell-to-cell fusion

The cleavage and fusion properties of recombinant murine hepatitis viruses (MHV) were examined to assess the role of the cleavage signal in determining the extent of S protein cleavage, and the correlation between cleavage and induction of cell-to-cell fusion. Targeted recombination was used to intr...

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Détails bibliographiques
Publié dans:J Neurovirol
Auteurs principaux: Hingley, Susan T., Leparc-Goffart, Isabelle, Seo, Su-hun, Tsai, Jean C., Weiss, Susan R.
Format: Artigo
Langue:Inglês
Publié: Springer-Verlag 2002
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7095328/
https://ncbi.nlm.nih.gov/pubmed/12402166
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/13550280260422703
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