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A combination of mutations in the S1 part of the spike glycoprotein gene of coronavirus MHV-A59 abolishes demyelination

The A59 strain of coronavirus, mouse hepatitis virus (MHV), produces acute hepatitis, meningoencephalitis, and chronic demyelination. The authors have previously shown that the spike (S) glycoprotein gene of MHV contains determinants of virulence, hepatitis, and demyelination. They then identified v...

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Detalhes bibliográficos
Publicado no:J Neurovirol
Main Authors: Fu, Li, Gonzales, Donna M., Das Sarma, Jayasri, Lavi, Ehud
Formato: Artigo
Idioma:Inglês
Publicado em: Springer-Verlag 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7095319/
https://ncbi.nlm.nih.gov/pubmed/14982727
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/13550280490262229
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