Endothelial protein C receptor polymorphisms and risk of severe sepsis in critically ill patients

PURPOSE: Endothelial protein C receptor (EPCR) is expressed mainly in endothelial cells and is involved in regulation of the cytoprotective and anticoagulant pathways of protein C. We assessed whether haplotypes in the EPCR gene modify the risk of severe sepsis and/or septic shock (SS/SS) developmen...

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Publicado en:Intensive Care Med
Main Authors: Vassiliou, Alice G., Maniatis, Nikolaos A., Kotanidou, Anastasia, Kallergi, Marina, Karystinaki, Foteini S., Letsiou, Eleftheria, Glynos, Constantinos, Kopterides, Petros, Vassiliadi, Dimitra, Nikitas, Nikitas, Dimopoulou, Ioanna, Armaganidis, Apostolos, Orfanos, Stylianos E.
Formato: Artigo
Idioma:Inglês
Publicado: Springer Berlin Heidelberg 2013
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Original
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7095157/
https://ncbi.nlm.nih.gov/pubmed/23881209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00134-013-3018-5
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