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Neither B cells nor T cells are required for CNS demyelination in mice persistently infected with MHV-A59

Murine hepatitis virus A59 infection of the central nervous system (CNS) results in CNS demyelination in susceptible strains of mice. In infected B-cell-deficient mice, demyelination not only occurred but was also more severe than in parental C57BL/6 animals. This increase may be due to the persiste...

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Detalhes bibliográficos
Publicado no:J Neurovirol
Main Authors: Matthews, A. E., Lavi, E., Weiss, S. R., Paterson, Y.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer-Verlag 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7095043/
https://ncbi.nlm.nih.gov/pubmed/12053280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/13550280290049697
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